Effect of Vitamin D Supplementation on Clinical and Radiographic Evaluation of Oral Rehabilitation with Osseointegrated Implants

  • Adriano Piccolotto Student, Stricto Sensu Graduate Program in Dentistry. Universidade Estadual do Oeste do Paraná, Cascavel, Brazil.
  • Gisele Toyama Student, Stricto Sensu Graduate Program in Dentistry. Universidade Estadual do Oeste do Paraná, Cascavel, Brazil.
  • Mauro Busato PhD, Professor, Stricto Sensu Graduate Program in Dentistry. Universidade Estadual do Oeste do Paraná, Cascavel, Brazil.
  • Adriane Yaeko Togashi PhD, Professor. Associate. Stricto Sensu Graduate Program in Dentistry. Universidade Estadual do Oeste do Paraná, Cascavel, Brazil.

Resumo

Abstract  

Vitamin D (VD) is important for the development and maintenance of bone tissue. This study used clinical and radiographic evaluations to analyze whether insufficient VD levels affect the periimplant health of patients with implant-supported prostheses. Data were collected for 33 patients with implant-supported prostheses: probing depth (PD); width of keratinized mucosa (wKM); bleeding index (mBI); periimplant plaque index (mPI); distance from implant to bone crest and VD level using chemiluminescence. After 1 year of implant-supported prosthesis installation, patients with levels under 30 ng/ml at baseline received 50000 IU of VD per week for 8 weeks (post treatment, PT), when clinical and radiographic evaluations were repeated for the control (n=19) and the VD (n=14) groups. Clinical and radiographic results were compared at baseline and at PT.  There were differences in PD (p=0.0247) and distance from implant to bone crest (p<0.0001), but there were not statistically different after supplementation.  wMK, mBI and mPI were not statistically different between groups.  VD levels were 24.95 ± 0.96 ng/mL in the VD group (42.42% of patients), whereas 57.57% of all participants had a mean VD value of 40.99 ± 1.23 ng/mL, a statistically significant difference (p = 0.0034). According to clinical and radiographic findings, VD serum levels do not seem to affect periimplant health.

 

Keywords: Bone Density. Clinical Study. Dental Implantation.

 

Resumo

A vitamina D (VD) é importante para o desenvolvimento e a manutenção do tecido ósseo. Este estudo clínico e radiográfico avaliou a reposição dos níveis de vitamina D na saúde periimplantar de pacientes com próteses implantossuportadas. Profundidade bolsa a sondagem (PS), largura da mucosa queratinizada (LMQ), sangramento a sondagem (mBI), presença de placa bacteriana (mPI), distância entre implante e cristas ósseas e dosagem de VD utilizando o teste de quimioluminescência, foram medidos em 33 pacientes. Pacientes com dosagens acima de 30 ng/ml foram classificados como suficientes de VD (grupo controle, n = 19). Pacientes com menos de 30ng/ml (grupo VD, n = 14) receberam, após 1 ano da instalação da prótese sobre implante, reposição de 50.000 UI por semana durante 8 semanas, quando os exames foram repetidos. Dados iniciais intragrupos, bem como dados iniciais e pós-tratamento (PT) intergrupos e intragrupos, foram comparados. Diferenças estatísticas foram encontradas em PS (p=0.0247) e distância entre crista óssea e implante (p<0.0001) entre os grupos, mas não após reposição. Não houve diferença em LMQ, mBI e mPI entre os grupos. O valor médio de VD do grupo VD foi 24,95±0.96 ng/ml para 42,42% dos pacientes, enquanto 57,57% da amostra apresentaram valor médio de 40,99±1.23 ng/ml, demonstrando diferença estatística (p=0.0034). A reposição de VD não parece influenciar os achados clínicos e radiográficos da saúde periimplantar.

 

Palavras-chave: Densidade Óssea. Estudo Clínico. Implantação Dentária.

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Publicado
2019-12-20